Sensible Medicine

Sensible Medicine

Are SSRIs Good or Evil?

A 1st, 2nd, and 3rd opinion

Adam Cifu, MD's avatar
Vinay Prasad's avatar
John Mandrola's avatar
Adam Cifu, MD, Vinay Prasad, and John Mandrola
Jul 08, 2026
∙ Paid

The HHS Secretary has been critical of how many people take SSRIs for lengthy durations and how, for a subset, discontinuing the medications may be difficult. In contrast, some psychiatrists swear by the medications, reporting anecdotal cases of dramatic improvement. Here, as part of our first, second and third opinion series we provide three takes on the question: Are SSRIs good or evil?

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