19 Comments
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Jake Kelly MD's avatar

Great article. Great review by Dr. Anil Makam. I look forward to learning more and following along.

Trilety Wade's avatar

The gabapentin study and wound vac study were super interesting!

Petya G's avatar

Outstanding! Thank you !

Alan's avatar

This is about the best summary of major articles, some I have missed, ever! You beat all my NEJM Journal Club and JAMA subscriptions hands down. Wonderful summary.

Thank you!

Julia's avatar

Great post. Appropriate audience reached and fully satisfied. We’ll pass on to other colleagues in IM, critical care, derm, plastics.

lsmg's avatar

As a hospital Surgicalist, I read the Lancet article about NPWT. Was heavily (>90%) skewed to post vascular surgery lower extremity wounds, so cannot be interpreted for all surgical wounds as that is a very specific patient class. I know you are an internist, but maybe don't add a generalized statement on a surgical subject?

Rachel Johnson, MD's avatar

Very nice recap, and I love your category choices! Your thread on X was the first I'd heard of the Olezarsen trial. We see a handful of HyperTG pancreatitis each year. I'm expecting I won't be able to prescribe at discharge, as it feels like the type of med that will require a PA from a specialist (at least for now)

Great work!

Carl Blesch's avatar

What a superb and thoroughly readable summary! For people who don’t get the acronyms, do what I did: take 10 seconds and look them up! You’ll learn something.

David Dierkes's avatar

The vitamin K levels were very interesting. I have afib for many years and mostly have a fewer episodes since taking K 3 with D. Very interesting and I’m definitely keeping it up!

Stephen Hughes's avatar

If you want to reach a wider audience, please stop using acronyms

Adam Cifu, MD's avatar

Added “translations

Robert Eidus's avatar

Loved it and I do not even do hospital work

Thsnks

Brock Jones's avatar

Love this, lots of actionable studies that are applicable to commonly seen patient populations. Will definitely be referencing this in the future!

Seneca Plutarchus's avatar

A lot of these are more out of the hospital issues.

jack dowie's avatar

Great summaries Anil, but I'm struggling with the Makam paper.. Sure, doctors should strive to be pathognomonic in every case, but until they are it is vital that even those with the greatest AUROC personal curve accept the need to make a preference-based trade-off. Maximising both Se and Sp (e,g, by Youden )will almost never be optimal.

Tina C's avatar

BOOM. There it is. Awesome

Eva's avatar

Wonderful summary, thank you! One I will for sure file away for my library of references.