Sensible Medicine

Sensible Medicine

What Would Warrant a Vaccine Mandate in the United States Today

Adam Cifu, MD's avatar
Adam Cifu, MD
Oct 17, 2025
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Writing about vaccine mandates in 2025 seems a bit insane. It might even be enough to get one placed on some academic faculty watch list. Maybe, though, it’s the perfect time to think about vaccine mandates. Considering a new vaccine for adults, what would warrant a vaccine mandate in the United States today? What would make it politically acceptable? When might they be considered? What factors would need to be weighed when balancing benefits and harms?

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