Really appreciate you covering this topic as I work in this industry. This paper from the Pathfinder study is what I would call putting Galleri truly in the field as a screening assay, ie phase IV. These assays never perform as well when using “known” samples. In this paper they even stratify by age as you would expect detected cancer ca…
Really appreciate you covering this topic as I work in this industry. This paper from the Pathfinder study is what I would call putting Galleri truly in the field as a screening assay, ie phase IV. These assays never perform as well when using “known” samples. In this paper they even stratify by age as you would expect detected cancer cases to go up. But you can see sensitivity is even lower…
Really appreciate you covering this topic as I work in this industry. This paper from the Pathfinder study is what I would call putting Galleri truly in the field as a screening assay, ie phase IV. These assays never perform as well when using “known” samples. In this paper they even stratify by age as you would expect detected cancer cases to go up. But you can see sensitivity is even lower…
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01700-2/abstract