"I would argue that the HERS and WHI trials are far more important. They showed that the observational data suggesting cardiac benefits from hormone replacement therapy were wrong."
So, a reduced death rate in women 50-60 y/o on estrogen means there are no cardiac benefits? WHI suffered from a very wide age distribution in women started o…
"I would argue that the HERS and WHI trials are far more important. They showed that the observational data suggesting cardiac benefits from hormone replacement therapy were wrong."
So, a reduced death rate in women 50-60 y/o on estrogen means there are no cardiac benefits? WHI suffered from a very wide age distribution in women started on HT, something that basically almost never happened in the real world, at least not in the world inhabited by OBGs as am I. There is an optimum age to give HT, and an age beyond which other measures should be considered. Clarifying the difference is important. Making blanket statements is not helpful. Even Joanne Munson changed her views on the WHI results as more detailed analysis showed who benefited and who didn't from HT.
"I would argue that the HERS and WHI trials are far more important. They showed that the observational data suggesting cardiac benefits from hormone replacement therapy were wrong."
So, a reduced death rate in women 50-60 y/o on estrogen means there are no cardiac benefits? WHI suffered from a very wide age distribution in women started on HT, something that basically almost never happened in the real world, at least not in the world inhabited by OBGs as am I. There is an optimum age to give HT, and an age beyond which other measures should be considered. Clarifying the difference is important. Making blanket statements is not helpful. Even Joanne Munson changed her views on the WHI results as more detailed analysis showed who benefited and who didn't from HT.