Interesting article. For the most part I agree with the conclusions. However, my takeaway is what I notice missing most from study design, is the lack of instructive distinctions in the host population. We are not all the same. Precision Medicine was supposed to address this by focusing more on the individual, but I think that has tur…
Interesting article. For the most part I agree with the conclusions. However, my takeaway is what I notice missing most from study design, is the lack of instructive distinctions in the host population. We are not all the same. Precision Medicine was supposed to address this by focusing more on the individual, but I think that has turned into window dressing and a way for corporate medicine to pretend they are actually following some of functional medicine principles efforts to find root causes, when in reality they are not. Perhaps it is NOT so much the input, but rather the health of the host which protects the body from various insults along the way. I'm not just referring to age, gender and ethnicity host variables, though those are important. I would like to see study distinctions such as microbial diversity in the gut microbiome, C section vs vaginal, breast-fed vs not breast-fed and for how long, vaccinated and unvaccinated, delayed vaccination, selective vaccination, age at first vaccination, autoimmunity or cancer in the immediate family as study variables.
Interesting article. For the most part I agree with the conclusions. However, my takeaway is what I notice missing most from study design, is the lack of instructive distinctions in the host population. We are not all the same. Precision Medicine was supposed to address this by focusing more on the individual, but I think that has turned into window dressing and a way for corporate medicine to pretend they are actually following some of functional medicine principles efforts to find root causes, when in reality they are not. Perhaps it is NOT so much the input, but rather the health of the host which protects the body from various insults along the way. I'm not just referring to age, gender and ethnicity host variables, though those are important. I would like to see study distinctions such as microbial diversity in the gut microbiome, C section vs vaginal, breast-fed vs not breast-fed and for how long, vaccinated and unvaccinated, delayed vaccination, selective vaccination, age at first vaccination, autoimmunity or cancer in the immediate family as study variables.