Study of the Week is over at Stop and Think

Oct 30, 2023

Hi all. I thought I could write the Study-of-the-Week on Stop and Think and simply cross post it here. But. Sadly.

My Substack skills are lacking. Sorry.

Here is the link to my column: It was a fun topic.

If only critical appraisal was this good for *all* studies

Let’s start with a picture: This is the Kaplan-Meier curve, from an RCT, published in JAMA, of an oral medication vs a placebo given to patients after a myocardial infarction (MI). The group on the drug sustained a 36% reduction in the occurrence a major adverse cardiac or brain event vs placebo. Outcomes included cardiac death, MI, emergency coronary r…

a year ago · 1 like · John Mandrola

And. A screenshot:

Sobshrink

While it may not be ready yet, I hope an algorithm can be developed for AI that will evaluate all medical research using the same criteria, so that human bias can be removed. But only humans can decide whether a difference between groups is clinically meaningful, especially at an individual (not population) level.

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Toolste

Would one of the Ai criteria be :

Cina bad?

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Sensible Medicine

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