Re colon cancer screening, one might conclude that the incidence is so low, and disease specific mortality so low, that no screening test will ever be useful. I usually recommend FOBT for average risk since it's cheap and easy. Colonoscopy for all makes no sense except to the gastroenterologists.
Thanks for the discussion, I really enjoy this series! If you guys have a chance, would you consider taking a look at SERENA-6 from ASCO?
https://www.nejm.org/doi/abs/10.1056/NEJMoa2502929
Very nice discussion.
Re colon cancer screening, one might conclude that the incidence is so low, and disease specific mortality so low, that no screening test will ever be useful. I usually recommend FOBT for average risk since it's cheap and easy. Colonoscopy for all makes no sense except to the gastroenterologists.