This Fortnight in Medicine XI

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This Fortnight in Medicine XI

Is Adam wrong about dementia prevention? What about that U-shaped relationship between cholesterol and mortality? Can three people who agree argue about the benefits of statins?

Adam Cifu, MD, John Mandrola, and Andrew J Foy

Oct 22, 2025

Total cholesterol and all-cause mortality by sex and age: a prospective cohort study among 12.8 million adults

The Ideal Cholesterol Level ... Depends...And Cannot Be Determined From Observational Studies

Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial

Can We Please Stop Asking if Crossword Puzzles Prevent Dementia?

Sensible Medicine

This Fortnight in Medicine XI

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