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HardeeHo's avatar

"Probably ineffective once you have symptoms. Viremia occurs before symptom onset." That's why whenever I venture out, I include the sanitation as a routine, much like brushing my teeth. Not waiting for symptoms.

If I develop symptoms, I would turn to the FLCCC protocols. I would need to be on death's door before going to the hospital. I just hope that won't happen.

Pity that study hasn't quite reached far enough. I recall that poor Princess Cruise guy that kept PCR testing positive in Omaha and it was quite some time before they released him. In those early days the docs were quite confused. I suspect there remain a lot still uniformed.

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Tom Hogan's avatar

Raoult is a controversial figure. He's brilliant, but sometimes careless about his rationale for doing things. He's virtually the only guy who publishes papers where he used culturing virus as part of his method--brilliant. If Pfizer had cultured virus from everyone who had symptoms of influenza, we'd probably see efficacy around 15% or maybe negative.

In case any one wonders, I wasn't making up the stuff about viremia occurring before symptom onset in covid patients.

"Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia"

https://www.nature.com/articles/s41409-020-01059-y

These IM docs probably don't know much about covid that occurs before they see patients, but that doesn't stop them from making asinine comments about early treatment with "fake" therapeutics or understanding much about the diagnosis of mild covid. These guys think that their clinical hospital experience somehow carries over to community care (outpatient treatment).

They quack me up.

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HardeeHo's avatar

I don't know flu doubling time, but SARs-2 is ~ 3 days or so. Sanitation should be able to stop replication before the load doubles.

The doubling time is why culture is just so slow, thus expensive mainly because of all the logistics involved.

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Tom Hogan's avatar

Culturing isn't useful for clinical practice, but it's very useful for research. Culturing _could_ have been done in vaccine efficacy trials, but wasn't, likely because the research designers knew that culturing would have a negative impact on vaccine efficacy calculation.

There were estimates of false negative rates published, so if researchers had applied those ostimates to the number of tests performed, then an estimate of false positives could have been calculated. If culturing had been done, then researchers would have known exactly how many false negatives there were and could have added the false negatives to the total count of covid cases for each arm.

Why is Pfizer hiding the total number of covid tests that were performed?

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