While rounding on an inpatient service, Dr. Anil Makam noticed positive news about COVID-19. Many of his online colleagues did not appreciate these upbeat observations
Increasing SARS-CoV2 cases, hospitalizations and deaths among the vaccinated elderly populations during the Omicron (B.1.1.529) variant surge in UK.
Figure 6: The proportionality test results detailed in Tables S8(a-f); show a significantly higher proportion of SARS-CoV2 hospitalizations in all vaccinated population (including the third dose) than the unvaccinated among ≥18 years of age and ≥50 years of age during the latter part of the Omicron variant surge. https://www.medrxiv.org/content/10.1101/2022.06.28.22276926v1.full.pdf
Public Health Scotland COVID-19 & Winter Statistical Report As at 17January 2022
I was an original liker of the tweet. It was obvious that you meant severe covid was gone vis a vis the patients you saw, not that severe covid in the world was gone.
Thanks for the clarification. I didn't interpret what you originally said as something generalizable. Also, I took your tweet in the spirit in which you wrote it: here is something great that just happened!
I admire your courage to speak out. I suspect this crowd will dispute some of your assertions. It's a pity we can't have dispassionate referees. From my research I feel I may have been damaged by the two shots in early days before data. I had no idea that mouth and nose sanitation might be effective to reduce viral loads before replication really gets going. I was somewhat aware of HCQ and finally obtained some, just in case, but that treatment was unknown in early days. I eventually added some IVM to my shelf of just in case. Given I'm 82 with COPD, I've learned to be prudent and avoid crowds.
As I see it the earliest days were tragic with a lot of bad advice and difficult times for those entering the hospital given there was no treatment protocol. The panic that took over caused many to lose their minds out of fear. Who knows how many were injured just from the stress? Fear is abating and it really is a time for reflection. Data prove that the efforts to mitigate spread were ineffective. Aside from that we have now vaccines of dubious utility. I remain sad that simple preventative measures were never promoted. As Prasad constantly notes where are the RCTs?
Get your 25OHD levels up (which implies testing them, of course) and stock some calcifediol in your cabinet and you should be fine.
I'm elderly and go to bars and restaurants. I keep calcifediol stocked and elderberry concentrate in the fridge. Its use is backed by RCTs for RNA viruses to reduce symptom duration by a couple of days and it has known antiviral action via quercetin and zinc as well as immunomodulatory properties.
"I had no idea that mouth and nose sanitation might be effective to reduce viral loads before replication really gets going."
Probably ineffective once you have symptoms. Viremia occurs before symptom onset. Most of these internal medicine docs won't know that, of course. But they'll pontificate that HCQ and IVM don't work when given to outpatients without ever having tried them to treat outpatients. (Early, of course).
If you want to understand viral load, check out
"Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards"
"Probably ineffective once you have symptoms. Viremia occurs before symptom onset." That's why whenever I venture out, I include the sanitation as a routine, much like brushing my teeth. Not waiting for symptoms.
If I develop symptoms, I would turn to the FLCCC protocols. I would need to be on death's door before going to the hospital. I just hope that won't happen.
Pity that study hasn't quite reached far enough. I recall that poor Princess Cruise guy that kept PCR testing positive in Omaha and it was quite some time before they released him. In those early days the docs were quite confused. I suspect there remain a lot still uniformed.
Raoult is a controversial figure. He's brilliant, but sometimes careless about his rationale for doing things. He's virtually the only guy who publishes papers where he used culturing virus as part of his method--brilliant. If Pfizer had cultured virus from everyone who had symptoms of influenza, we'd probably see efficacy around 15% or maybe negative.
In case any one wonders, I wasn't making up the stuff about viremia occurring before symptom onset in covid patients.
"Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia"
These IM docs probably don't know much about covid that occurs before they see patients, but that doesn't stop them from making asinine comments about early treatment with "fake" therapeutics or understanding much about the diagnosis of mild covid. These guys think that their clinical hospital experience somehow carries over to community care (outpatient treatment).
Culturing isn't useful for clinical practice, but it's very useful for research. Culturing _could_ have been done in vaccine efficacy trials, but wasn't, likely because the research designers knew that culturing would have a negative impact on vaccine efficacy calculation.
There were estimates of false negative rates published, so if researchers had applied those ostimates to the number of tests performed, then an estimate of false positives could have been calculated. If culturing had been done, then researchers would have known exactly how many false negatives there were and could have added the false negatives to the total count of covid cases for each arm.
Why is Pfizer hiding the total number of covid tests that were performed?
85+ y.o. mortality increased 23% in 2020 over 2019 caused by covid, followed by a 14% decline in 85+ y.o. mortality in 2021 over 2020 as those who were vulnerable in the 85+ y.o. group were culled the previous year.
This explains lower CFR and lower hospitalization rates.
You don't have to apologize. Any sane person would have taken it exactly as written "severe covid is gone" . But if people are still worshiping a the alter of Covid, that's their problem.
The assertion has been made that the drop in case fatality rate for covid was due to vaccines. Certainly, there are several confounders.
Perhaps the most significant confounder is that in 2021, the mortality of the 85+ y.o. group plummeted 14% after peaking in 2020. This is where we have actual data, unlike for the assertion of CFR reduction by vaccines.
Using the same logic as in the pro-vaccine assertion, vaccines are responsible for the 18% increase in working age mortality in 2021 over 2020, which is a six sigma variance in the working age mortality data.
The more extreme elements control the microphone. They won't let Dr. Malone speak, either, because he has noticed that the Emperor's New Clothes aren't to be seen.
The more positve news is the return of the flu after 2 year of worldwided absence...
That's a miracle!
Thank you, Dr. Makam. Many of us are with you and are grateful for your message.
"miracle of COVID-19 vaccines"
Increasing SARS-CoV2 cases, hospitalizations and deaths among the vaccinated elderly populations during the Omicron (B.1.1.529) variant surge in UK.
Figure 6: The proportionality test results detailed in Tables S8(a-f); show a significantly higher proportion of SARS-CoV2 hospitalizations in all vaccinated population (including the third dose) than the unvaccinated among ≥18 years of age and ≥50 years of age during the latter part of the Omicron variant surge. https://www.medrxiv.org/content/10.1101/2022.06.28.22276926v1.full.pdf
Public Health Scotland COVID-19 & Winter Statistical Report As at 17January 2022
Table 16: Number of confirmed COVID-19 related deaths by vaccination status at time of test and age-standardised mortality rate per 100,000, 11 December 2021 to 07 January 2022 https://web.archive.org/web/20220217202938/https://publichealthscotland.scot/media/11223/22-01-19-covid19-winter_publication_report.pdf
COVID vaccination and age-stratified all-cause mortality risk (USA and Europe)
Vaccination correlated negatively with mortality 6-20 weeks post-injection, while vaccination predicted all-cause mortality 0-5 weeks post-injection in almost all age groups and with an age-related temporal pattern consistent with the US vaccine rollout. https://www.researchgate.net/publication/355581860_COVID_vaccination_and_age-stratified_all-cause_mortality_risk
Excess Mortality in Germany 2020-2022
Fig. 5: Yearly excess mortality. The red bars show the excess mortality in 2020 (left 389 panel) and 2021 (right panel) in different age groups, which shows an increase in 2021 for all age groups above 60. https://www.researchgate.net/publication/362777743_Excess_mortality_in_Germany_2020-2022
What a sensible article! Truly shocking, lol!
I was an original liker of the tweet. It was obvious that you meant severe covid was gone vis a vis the patients you saw, not that severe covid in the world was gone.
The vaccines are toxic garbage and you aided and abetted fascists by worshiping it.
I hope the bigger fanatics punish your heresy accordingly.
How many of you guys think that the docs posting and commenting here actually know anything about mild covid and treating it?
Do you think that any of them have actually tried treating covid early or talked with physician PCPs about it?
Let me know what you think.
You lost me when you Tweeted you wish you would have recommended masks earlier.
What is the dosing on masks? Or are they a surgical or radiological intervention? I forget.
These nimrods can't even tell when they are out of field.
Thanks for the clarification. I didn't interpret what you originally said as something generalizable. Also, I took your tweet in the spirit in which you wrote it: here is something great that just happened!
I admire your courage to speak out. I suspect this crowd will dispute some of your assertions. It's a pity we can't have dispassionate referees. From my research I feel I may have been damaged by the two shots in early days before data. I had no idea that mouth and nose sanitation might be effective to reduce viral loads before replication really gets going. I was somewhat aware of HCQ and finally obtained some, just in case, but that treatment was unknown in early days. I eventually added some IVM to my shelf of just in case. Given I'm 82 with COPD, I've learned to be prudent and avoid crowds.
As I see it the earliest days were tragic with a lot of bad advice and difficult times for those entering the hospital given there was no treatment protocol. The panic that took over caused many to lose their minds out of fear. Who knows how many were injured just from the stress? Fear is abating and it really is a time for reflection. Data prove that the efforts to mitigate spread were ineffective. Aside from that we have now vaccines of dubious utility. I remain sad that simple preventative measures were never promoted. As Prasad constantly notes where are the RCTs?
Get your 25OHD levels up (which implies testing them, of course) and stock some calcifediol in your cabinet and you should be fine.
I'm elderly and go to bars and restaurants. I keep calcifediol stocked and elderberry concentrate in the fridge. Its use is backed by RCTs for RNA viruses to reduce symptom duration by a couple of days and it has known antiviral action via quercetin and zinc as well as immunomodulatory properties.
"I had no idea that mouth and nose sanitation might be effective to reduce viral loads before replication really gets going."
Probably ineffective once you have symptoms. Viremia occurs before symptom onset. Most of these internal medicine docs won't know that, of course. But they'll pontificate that HCQ and IVM don't work when given to outpatients without ever having tried them to treat outpatients. (Early, of course).
If you want to understand viral load, check out
"Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards"
https://link.springer.com/article/10.1007/s10096-020-03913-9
"Probably ineffective once you have symptoms. Viremia occurs before symptom onset." That's why whenever I venture out, I include the sanitation as a routine, much like brushing my teeth. Not waiting for symptoms.
If I develop symptoms, I would turn to the FLCCC protocols. I would need to be on death's door before going to the hospital. I just hope that won't happen.
Pity that study hasn't quite reached far enough. I recall that poor Princess Cruise guy that kept PCR testing positive in Omaha and it was quite some time before they released him. In those early days the docs were quite confused. I suspect there remain a lot still uniformed.
Raoult is a controversial figure. He's brilliant, but sometimes careless about his rationale for doing things. He's virtually the only guy who publishes papers where he used culturing virus as part of his method--brilliant. If Pfizer had cultured virus from everyone who had symptoms of influenza, we'd probably see efficacy around 15% or maybe negative.
In case any one wonders, I wasn't making up the stuff about viremia occurring before symptom onset in covid patients.
"Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia"
https://www.nature.com/articles/s41409-020-01059-y
These IM docs probably don't know much about covid that occurs before they see patients, but that doesn't stop them from making asinine comments about early treatment with "fake" therapeutics or understanding much about the diagnosis of mild covid. These guys think that their clinical hospital experience somehow carries over to community care (outpatient treatment).
They quack me up.
I don't know flu doubling time, but SARs-2 is ~ 3 days or so. Sanitation should be able to stop replication before the load doubles.
The doubling time is why culture is just so slow, thus expensive mainly because of all the logistics involved.
Culturing isn't useful for clinical practice, but it's very useful for research. Culturing _could_ have been done in vaccine efficacy trials, but wasn't, likely because the research designers knew that culturing would have a negative impact on vaccine efficacy calculation.
There were estimates of false negative rates published, so if researchers had applied those ostimates to the number of tests performed, then an estimate of false positives could have been calculated. If culturing had been done, then researchers would have known exactly how many false negatives there were and could have added the false negatives to the total count of covid cases for each arm.
Why is Pfizer hiding the total number of covid tests that were performed?
Or read this...start at the beginning... https://coquindechien.substack.com/p/beaudoin-v-baker-governor-of-massachusetts
If you want to know about false COVID death data...here you go... https://metatron.substack.com/p/the-definitive-guide-to-covid-and
What is the Dry Tinder Effect for 400, Alex?
85+ y.o. mortality increased 23% in 2020 over 2019 caused by covid, followed by a 14% decline in 85+ y.o. mortality in 2021 over 2020 as those who were vulnerable in the 85+ y.o. group were culled the previous year.
This explains lower CFR and lower hospitalization rates.
You don't have to apologize. Any sane person would have taken it exactly as written "severe covid is gone" . But if people are still worshiping a the alter of Covid, that's their problem.
The assertion has been made that the drop in case fatality rate for covid was due to vaccines. Certainly, there are several confounders.
Perhaps the most significant confounder is that in 2021, the mortality of the 85+ y.o. group plummeted 14% after peaking in 2020. This is where we have actual data, unlike for the assertion of CFR reduction by vaccines.
Using the same logic as in the pro-vaccine assertion, vaccines are responsible for the 18% increase in working age mortality in 2021 over 2020, which is a six sigma variance in the working age mortality data.
The more extreme elements control the microphone. They won't let Dr. Malone speak, either, because he has noticed that the Emperor's New Clothes aren't to be seen.
https://rwmalonemd.substack.com/p/suppress-silence-skew-and-censor?isFreemail=true