31 Comments

It’s primarily a business decision for the journals. They are in it for profit, not for the betterment of science. Typically you try to publish a contrary result in a lower tier journal. Or you look for some new finding that supersedes what was published elsewhere.

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Children head bang. Pets head press.

All pet vaccines contain thimerosal/ mercury and are Not calibrated for weight.

How many wild animals do you see having seizures?

How common is it in dogs?

https://www.google.com/gasearch?q=why%20does%20my%20dog%20put%20its%20head%20against%20the%20wall?&source=sh/x/gs/m2/5

https://www.google.com/gasearch?q=are%20dog%20caccines%20callibrated%20for%20weight!&source=sh/x/gs/m2/5

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It seems to me that replication studies are very intellectually stimulating to read. When two research groups come to very different conclusions, trying to unwind the reasons for the disparities are some of the most intense, but intellectually satisfying exercises I have ever engaged in. I say publish the replications. Readers will thank you for them.

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The medical journals with paywalls to prevent the public from reading studies is a travesty to the public. Articles are sent to journalists who quote the results without any concern for the quality of the research. If I can't see the research article in full, I consider the results suspect.

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Thank you once again for posting another valuable article. I stopped reading much in the medical journals early in my career when I realized how corrupt and unscientific the great majority of the studies were. But I had no idea that there was an actual policy to not publish replication studies and was amazed that some of them even admitted as much. The general public (and, sadly, many in the medical profession) do not know the definition of science. They think of it as a body of knowledge. But science is simply a process for discovering truths in the physical world. Replications and refutations are not just interesting followups but are an absolutely essential part of the process. Without them it is not science.

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Think about this - how many of us have learned more from “failure” than success? In my own experience this has been true. Scientists get this. Sadly, those who pay the scientists don’t seem to. And therein lies the failure.

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The incentives in academic science re: publication are perverse.

I am in insurance industry research, and while negative results (no "there" there) are not exciting, I can publish about lack of correlations that people thought existed. They need to know that stuff -- and they will pay for that information.

No, it doesn't get me academic plaudits or tenure. It does get my company money.

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Blast from the past! I used to use The Infinite Actuary materials back in 2014. Can't believe I recognized your name here!

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Oh hey Kolby -- yeah I’ve got my own Substack writing about mortality and public pensions

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I just signed up! Still interested in those topics even though I no longer have any actuarial ambitions (I blame MFE for that... good riddance 😂)

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Ha - yeah, that's an ugly one.

And I see your sign up -- you read Glenn Loury, too! Great taste! ;)

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Since the article addresses correcting mistakes. I'll fix thie error in the article: "that the public may actually be right to be skeptical of science"

After COVID and VAX, I *KNOW* I'm right not to trust scientists/doctors/pharma and most of all, the shill or marketing arm of Pharma: FDA/CDC and prof org's for doctors including journals who now adopted the mandate of virtue signaling and narrative driven acceptance.

And I used to be the staunchest supporter of them. The trust bridge was burned beyond repair

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Same.

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I'm with you. After covid exposed the corruption in FDA and CDC I'm to the point where I think steering clear of the medical system is the best way to longevity, assuming you're eating well and getting exercise.

My primary doc wouldn't refill a script I've long had for Albuterol. Seasonal hay fever has plagued me all my life; I've always had asthma. But now she wants me to consult a pulmonologist so he can prescribe the inhaler. I won't. Instead I've found black tea actually works at opening the upper airways. Last ditch is ephedrine sulfate, still OTC. And I know if I went to a pulmonologist it's off to the races with tests and meds. Nope. I don't trust anyone in medicine.

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Very timely and important topic to be discussed and debated. The quick answer to the title is, No! Of Course not.

While reading into this essay, I was moving along nicely until I read the following line, and felt like I had just stepped into a large rusty nail with a barefoot, "Unsurprisingly, they found no effect". With only one word, "Unsurprisingly" the author inadvertently supports the hypothesis from Bem's study on precognition. All in all, though, a worthwhile read. I also agree with another commenter that the jab at those who suspect there beloved furry companions have been injured by a vaccine was negligent.

Will Sensible medicine please review the books, Turtles all the way Down and Dissolving Illusions.

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Sad that this is worse but to be honest many journals NEJM in particular have always been biased and agenda driven. My coworkers worked n a project published by a coinvestigator without consent and they misrepresented data. A letter to the editor was rejected as it didn't push the preferred narrative. I still cringe when anyone talks of COVID. After COVID, Dr. Fauci and his cohorts still wont reject the idea of building pathogens to infect humans that otherwise would not to "research" them. This is pure evil and one can study disease in the native species and learn all they need to know about pathogenesis without building another COVID pandemic. That pandemic was arrogance and the outcome predictable. Perhaps it was even by design.

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Great points reinforcing an endemic problem with Science. What about a journal that only accepted and published peer reviewed replication studies and retractions? Require that the title include the name of the original journal. Scarlet A’s all around.

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I am a lifetime subscriber of the New England Journal of Medicine. NEJM has embraced many editorial positions on abortion, gun violence as a public health issue, climate change, and for the Affordable Care Act. Despite the controversial positions, they have NEVER sought out contrary viewpoints for the sake of readers. The same is true for Nature, once a universally respected journal. This is essentially a boycott against conservative viewpoints.

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They’ve been corrupted for a long time. Once ads for pharma start in journals I no longer trust them.

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Yep NEJM has been corrupted to a narrative for decades.

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And yet it does not occur to them that their bias does not in some way violate the scientific method!

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Why hasn't anybody created a journal with the sole focus on negative results? I think there needs to be some incentive for researchers to get credit for their work even when their findings aren't significant.

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I agree that would be vitally important. Problem is there is no funding for that. Can you imagine the public response after learning that a vaccine wasn’t doing what the pharma folks said it would or should - oh wait...🤭

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I agree that it's not without issues. As somebody more familiar with social sciences, I'd like to see it in those contexts...i have wayyyy too much skepticism about the purported health benefits of birdsong and I suspect that many people who have studied the matter found no results and never published.

I think if it gains traction in social sciences we may start to see it in other contexts.

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What if there was a journal that did nothing but publish replications?

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I believe such a journal exists, but few pay attention to it.

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"37% of dog owners thought that vaccines might make their dog autistic." the incorrect perceived safety of vaccines should no longer be used to gaslight. they are inadequately tested with strong financial and legal incentives to maintain the status quo.

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I don't know what autism in dogs would look like, but I have personally met three people whose daughter/son/niece had regressive autism after vaccination. Given everything we're learning about the gut-brain-immune system relationship, it's pathetic the gas-lighting that is happening towards these families. I believe that if we stopped denying the link, and started investigating it, we could figure out how to prevent it, especially if it's related to microbiome health. In my family, the two non-Covid adverse vaccine reactions happened with a vaccine given a month after a round of antibiotics. If that's all that needs to stop - stop giving vaccines with or shortly after antibiotics and let the gut biome rebuild, then it's criminal that we continue to bury the subject at all.

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Yes! This is the larger underlying problem

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I don’t believe that vaccines could cause autism in dogs, however I don’t doubt that they might cause seizures in dogs. The vet even told me that could be the reason our Golden Retriever started having seizures. There needs to be more rigorous research into the safety of vaccines, for our pets as well as for ourselves. After my last flu shot, I developed a frightening stiffness in my legs and doctors at first feared GB. Thank God it wasn’t but my doctor said no more flu shots for me--ever. After that, I did a lot of research after blindly taking every vax that was recommended. (My father was a Harvard trained surgeon who touted the miracle of vaccines, so why wouldn’t I trust them?!) So yes, now I question the safety of vaccines.

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A significant fallout from Covid-19 experience is the unmasking of the arrogance and hubris of many in the academic/ governmental medical world. The loss of trust noted in medical care overall is due to lack of accountability and humility that has been exposed. Until this situation is very publicly acknowledged and corrected, there is no path to recovery. Unfortunately,it seems the individuals and organizations responsible have no intention of taking responsibility and correcting themselves,as they do not see this course as in their interests. What a sad world, now that so many publications have become the “ Journal of Irreproducible Results.” As we used to say of the Chairman;”often wrong, never in doubt.”

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