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A Trial of a Novel modRNA Flu Shot: Not So Hot
We are pleased to publish this guest critical appraisal of a recent influenza vaccine RCT--from Johns Hopkins cardiologist, Dr Joseph Marine
7 hrs ago
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Joseph Marine, MD
145
13
10
Who Do You Want at a Family Picnic?
If we want nice things, like functional primary care, we need to pay for them.
Jan 6
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Bradley Flansbaum
95
13
3
Prevention is a challenge in younger patients; it’s near impossible in older patients
Yet another study reveals the challenge of mechanical stroke prevention techniques, such as left atrial appendage closure, when applied to older…
Jan 5
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John Mandrola
119
27
5
The Ghost Patient Panel
Friday Reflection 23 Revisited
Jan 2
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Adam Cifu, MD
100
34
8
1:22:34
This Fortnight in Medicine XVI
Finishing up our AUA questions.
Dec 31, 2025
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Adam Cifu, MD
,
John Mandrola
, and
Andrew J Foy
34
5
2
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The COVID Vaccine in Young Children Is Not as Effective as the Headlines Would Have You Believe
COVID in kids made the news recently.
Dec 30, 2025
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Edward H Livingston, MD, FACS
142
32
4
Prediction is Hard Especially About the Future
Cardiac risk scores can be useful for populations but not so much for you.
Dec 29, 2025
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John Mandrola
130
64
10
For Christmas, A Gift of Laughter
...and a writing and editing break for me.
Dec 26, 2025
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Adam Cifu, MD
80
11
4
Holidays in the Hospital
It’s a common sentiment that working on a holiday is terrible but...
Dec 25, 2025
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Rachel Johnson
271
61
21
The Embarrassing but Necessary Lesson in a Drug Removal From the Market
Nearly everyone but Vinay Prasad was wrong about the Factor Xa reversal agent.
Dec 22, 2025
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John Mandrola
187
38
9
The Ethics of PSA Testing and Cancer Screening
Is choosing to undergo a screening like buying a lottery ticket in that you will not benefit, but you are helping someone else who might?
Dec 19, 2025
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Adam Cifu, MD
81
48
4
Climbing Out of the Trenches: Rethinking Polarisation in Medicine
We can choose to keep fighting from our ideological trenches—or we can collectively climb out of them. The path forward lies in recognising shared aims…
Dec 18, 2025
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Elspeth Davies
103
30
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Sensible Medicine
Common sense and original thinking in bio-medicine
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