Sensible Medicine | Substack

Staying True to Trial Analyses -- The Tale of Two Screening Trials

I contrast two population screening trials--DANCAVAS and NordICC. One stayed true to the principle of randomization. The other broke traditional…

17 hrs ago •

How JAMA Psychiatry Fooled Us About Antidepressant Withdrawal

Will Ward disagrees with my assessment of a JAMA-Psychiatry meta-analysis. His argument is persuasive and belongs on Sensible Medicine JMM

Aug 24 •

Friday Reflection 51: Failing in Place

When I am feeling self-assured, I can contend that aging is not a disease we can treat, that death is unavoidable, and that with even the most extreme…

Aug 22 •

The US POINTER trial was positive but mostly uninformative

Clinical trials in dementia are scarce but still need to be rigorous to help

Aug 21 •

32:57

How Not to Get Fooled by the Medical Literature - Part 9 - Trial design & Multiplicity

The most common question we get asked is: is there a course on how to become better at critically reading medical research.

Aug 20 •

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