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The award for the most unethical control arm in prostate cancer research in 2024 goes to: ARANOTE
A Sensible Medicine Guest Post
Sep 17 • 
Dries Develtere
81
8
Flawed Studies Teach Us a A Lot
As it is in math, repetition enhances learning. This week, we go over the problems with nonrandom comparisons, so called observational studies.
Sep 15 • 
John Mandrola
94
13
“You can observe a lot just by watching.” Yogi Berra
A Sensible Medicine Guest Post
Sep 13 • 
Robert Eidus
167
25
Friday Reflection 52: The Three Worst Phone Calls of My Career
A rookie mistake, a veteran mistake, and a patient’s unforced error
Sep 12 • 
Adam Cifu, MD
77
15
45:22
This Fortnight in Medicine VIII
Watch now | Last week, John was at the European Society of Cardiology conference in Madrid, and Adam was at the Preventing Overdiagnosis 2025…
Sep 10 • 
Adam Cifu, MD
 and 
John Mandrola
34
5
Evidence, The Elderly and Common Sense
A recent trial presented at the ESC meeting addresses the question of reducing blood pressure meds in the elderly. It’s an important study—for numerous…
Sep 8 • 
John Mandrola
166
37
Drink CEL! and Live Longer and Better
Dear Sensible Medicine subscriber, please share Part II of this post widely.
Sep 5 • 
Adam Cifu, MD
203
36
Blind Patients, Blind Doctors
How screening incentives worsen primary care
Sep 4 • 
Wil Ward
211
21
Please DO that research
A reply to the "ten topics that do not need to be studied"
Published on The Codon • Sep 2
This Year's ESC Meeting Had Lots of Great Trials
The Study of the Week takes Labor Day off--because I have been busy working at the ESC meeting. Here is a brief review.
Sep 1 • 
John Mandrola
64
5
Why the FDA’s COVID Vaccine Guidelines are Controversial
It seems we should all be able to agree, at the very least, that the FDA’s current approach makes us more likely to have better data in the coming…
Aug 30 • 
Adam Cifu, MD
118
48
Please do not do that research
Ten topics that do not need to be studied
Aug 29 • 
Adam Cifu, MD
316
56
Sensible Medicine
Sensible Medicine
Common sense and original thinking in bio-medicine
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