Sensible Medicine

Sensible Medicine

Home
Podcast
How Not To Get Fooled
Merch
Archive
About
Why the FDA’s COVID Vaccine Guidelines are Controversial
It seems we should all be able to agree, at the very least, that the FDA’s current approach makes us more likely to have better data in the coming…
 • 
Adam Cifu, MD
16
Please do not do that research
Ten topics that do not need to be studied
 • 
Adam Cifu, MD
50
No, The LA Fires Did Not Cause Excess Deaths as Reported in JAMA
A Sensible Medicine Guest Post
 • 
Edward H Livingston, MD, FACS
15
This Fortnight in Medicine VII
Do diabetes medications help arthritis or hurt the eyes?
 • 
Adam Cifu, MD
 and 
John Mandrola
2
39:45
Why AI Will Have Limited Impact on Population Health
A Sensible Medicine Guest Post
 • 
Howard Bauchner
11
Staying True to Trial Analyses -- The Tale of Two Screening Trials
I contrast two population screening trials--DANCAVAS and NordICC. One stayed true to the principle of randomization. The other broke traditional…
 • 
John Mandrola
18
How JAMA Psychiatry Fooled Us About Antidepressant Withdrawal
Will Ward disagrees with my assessment of a JAMA-Psychiatry meta-analysis. His argument is persuasive and belongs on Sensible Medicine JMM
 • 
Wil Ward
59
Friday Reflection 51: Failing in Place
When I am feeling self-assured, I can contend that aging is not a disease we can treat, that death is unavoidable, and that with even the most extreme…
 • 
Adam Cifu, MD
49
The US POINTER trial was positive but mostly uninformative
Clinical trials in dementia are scarce but still need to be rigorous to help
 • 
Clayton Mansel
11
How Not to Get Fooled by the Medical Literature - Part 9 - Trial design & Multiplicity
The most common question we get asked is: is there a course on how to become better at critically reading medical research.
 • 
Vinay Prasad
, 
Adam Cifu, MD
, and 
John Mandrola
4
32:57
One of Cardiology’s Most Positive and Most Ignored Trials
Perhaps it was the authors' choice of a complicated name. ISAR REACT 5 doesn’t stick in your brain, like CAST, or NOAH, or PLATO. But perhaps it’s a…
 • 
John Mandrola
14
Why don’t more people become living organ donors?
A Sensible Medicine Guest Post
 • 
Margaret Peterson
43
© 2025 Editors
Privacy ∙ Terms ∙ Collection notice
Start writingGet the app
Substack is the home for great culture