Archive - Sensible Medicine

Long COVID. Alzheimer’s. You Choose.

She had diagnosed herself by the time I saw her.

Apr 18 • Michael Sarai

Private-Mini-Memorials

All that I miss about the lives of my patients

Apr 17 • Adam Cifu, MD

An observational study for left atrial appendage closure supports CLOSURE AF data

Spring weather and travel attacked Sensible Medicine this week.

Apr 15 • Mohammed Ruzieh

Reckoning With COVID

Reflections on the Six-Year Anniversary of the COVID Outbreak in New York City

Apr 11 • Colleen Smith, MD

Guidelines, Evidence-based Medicine, and the Practice of Medicine

A meandering meditation on the flaws of guidelines and how evidence often barely affects practice

Apr 10 • Adam Cifu, MD

This Fortnight in Medicine XXIII

Listen now | Dengue Suppression by Male Wolbachia-Infected Mosquitoes

Apr 8 • Adam Cifu, MD, John Mandrola, and Andrew J Foy

33:33

The Illusion of Progression-Free Survival

We want patients to live longer and/or better, and if that’s not the case, keep “First, do no Harm” in mind.

Apr 7 • Dries Develtere

At ACC26, the HI-PEITHO Trial is in a Photo-Finish for Greatest Spin

Pulmonary embolism is a life-threatening condition that often requires more than anticoagulation. Invasive therapies hold promise but must be held to…

Apr 6 • John Mandrola

A Referendum on the Self: On Entering the Medical Profession

I could have been a much better pre-med. But I don’t think it would have made me a better doctor.

Apr 4 • Pradz Sapre

Hyponatremia, Observational Studies, and Changing Practice

and a whole lot of footnotes

Apr 3 • Adam Cifu, MD

March 2026

Physicians are Providers

Even if they are more than that

Mar 31

CHAMPION AF Breaks Almost Every Rule of Noninferiority Trial Design

Millions of people have AF and take oral anticoagulation. It's one of Medicine's most evidence-based treatments. It would take strong data to upend this…

Mar 30 • John Mandrola

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