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The Continuing Stream of Exercise Churnalism
This Fortnight in Medicine XXI
Incentives and Noninferiority Designs
Breaking News: I found a good observational study
Don’t ‘Break up Big Medicine’, Instead ‘Level the Playing Field’ and ‘Change the Game’.
The CV of Failures and the Unplanned Career Path
Last week I saw the end result of a biased trial, lax regulation, absent peer review and groupthink
Friday Reflection 58: COVID-19, Six Years On
A Little More on those Three Letters -- PSA
Primary prevention, statins, lottery effects and misinformation that is not actually misinformation
Alternative Modalities for Breast Cancer Screening
Tomosynthesis vs Digital Mammography Screening in Women with a Family History of Breast Cancer
Why Blood Tests Are a Poor Screening Tool for Alzheimer’s
Coffee is great but it does not prevent dementia
The Trouble with Treating the Future: Elevated Lipids, Low Risk, and the Making of Patients
In Honor of the Three Greatest Words in the English Language
The Doctor Won’t See You Now—Should You Worry?
This Fortnight in Medicine XIX
Initial Impressions of the LIBERATE-D Trial
Friday Reflection 57: Aging Is Not a Medical Problem
More Bad News for modRNA Vaccines
On the Conservation of Primary Care Physicians
The tension between expertise and convenience in complex medical care
Not a Bitter Pill to Swallow: A Simple Fix to Quell the Flu
This Fortnight in Medicine XVIII
How Good is the Apple Watch at Detecting Hypertension?
Exercise is great but exercise studies...not so much
Friday Reflection 56: Comments that Stuck
Another Thing That's Undeniably Improved in Medicine: Getting an HIV Test
Prostate Cancer Screening: Lessons from Plato on Justice and Communication
FAME-2: One of cardiology's most influential trials, and, one of its most flawed
When to treat (or not treat) a high cholesterol
Learning Medicine Requires Learning a New Language
The Best Studies of 2025 for Hospital Medicine
This Fortnight in Medicine XVII
2024-2025 COVID-19 Vaccine Effectiveness in Pediatric Patients: A Response
Food may be medicine but it is not an easy one to give nor is it very effective
Why Healthcare Commentators (and Doctors) are Afraid of the Free-Market
A Trial of a Novel modRNA Flu Shot: Not So Hot
Who Do You Want at a Family Picnic?
Prevention is a challenge in younger patients; it’s near impossible in older patients